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  • SHINING A LIGHT ON XERODERMA PIGMENTOSUM - PMC
    Xeroderma pigmentosum (XP) is a rare, autosomal recessive disorder of DNA repair characterized by sun sensitivity and ultraviolet (UV) induced skin and mucous membrane cancers Described in 1874 by Moriz Kaposi in Vienna, nearly 100 years later
  • Xeroderma Pigmentosum Clinical Presentation: History, Physical . . .
    Xeroderma pigmentosum (XP) was first described in 1874 by Hebra and Kaposi In 1882, Kaposi coined the term xeroderma pigmentosum for the condition, referring to its characteristic dry,
  • Xeroderma pigmentosum - Wikipedia
    Xeroderma pigmentosum was first described in 1874 by Hebra and Moritz Kaposi In 1882, Kaposi coined the term xeroderma pigmentosum for the condition, referring to its characteristic dry, pigmented skin [citation needed]
  • Xeroderma pigmentosum: a review and case series - ScienceDirect
    The disorder was first called “xeroderma or parchment skin” and in 1882, the term “pigmentosum” was added to emphasize the striking pigmentary abnormality (Kaposi, 1883)
  • Xeroderma Pigmentosum - geneskin. org
    Xeroderma pigmentosum (XP) is an autosomal recessive disorder first described by Moriz Kaposi in Ferdinand von Hebra's textbook of Dermatology published in 1870 The term “xeroderma pigmentosum” refers to the dry and pigmented skin typically present in affected individuals
  • Xeroderma pigmentosum - Altmeyers Encyclopedia - Department Dermatology
    It was not until 20 years later that the term "xeroderma pigmentosum" was coined In 1968, it was demonstrated by James Cleaver that the cells of these patients had a defect in DNA repair genes, the nucleotide excision repair (NER) system
  • Xeroderma pigmentosum | Health and Medicine - EBSCO
    This condition is caused by mutations in genes responsible for DNA repair, specifically those involved in nucleotide excision repair There are several classes of xeroderma pigmentosum, each with varying severity and associated risks
  • Xeroderma pigmentosum: an updated review - PMC
    Early recognition of xeroderma pigmentosum is important to minimize the complications arising from the harmful effects of exposure to ultraviolet radiation This narrative review aims to familiarize physicians with the clinical features, diagnosis and management of xeroderma pigmentosum
  • Forty Years of Research on Xeroderma Pigmentosum at the US National . . .
    Dr Robbins began studying XP patients with Dr Peter Burk, a Clinical Associate in the Dermatology Branch, and investigating their clinical features and DNA repair levels They developed a rapid in vitro method to study DNA repair in peripheral blood lymphocytes treated with UV
  • Xeroderma pigmentosum: the first of the cellular caretakers
    In 1967, in a fallow moment, I read about a hereditary human cancer, xeroderma pigmentosum (XP), not in a learned journal, but in an article of the San Francisco Chronicle written by science journalist David Perlman





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