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  • Symptoms, diagnosis and treatment - BMJ Best Practice
    Patients are often asymptomatic or have only mild gastrointestinal symptoms at initial presentation Untreated acetaminophen poisoning may cause varying degrees of liver injury over the 1 to 4 days following ingestion, including fulminant hepatic failure Rarely, massive overdose may initially present with coma and severe metabolic acidosis
  • Paracetamol overdose in adults - Symptoms, diagnosis and treatment . . .
    Paracetamol overdose may occur after excessive ingestion of paracetamol or paracetamol-containing medication as an acute or staggered overdose, or therapeutic excess Patients are often asymptomatic or have only mild gastrointestinal symptoms at initial presentation Untreated paracetamol poisoning m
  • Symptoms, diagnosis and treatment - BMJ Best Practice
    Acute toxicity may occur after ingestion of a single dose of aspirin or the equivalent of >150 mg kg or >6 5 g [2] Chronic poisoning tends to occur as a result of repeated exposure to high-dose aspirin or equivalent (150 mg kg day), particularly in people with renal insufficiency
  • Digoxin toxicity - Symptoms, diagnosis and treatment | BMJ Best Practice
    Digoxin toxicity may be acute, acute on chronic, or chronic Overdose can occur either intentionally or accidentally Typically presents with components of gastrointestinal, constitutional, and or cardiovascular symptoms Diagnosis is based on symptoms and laboratory data At therapeutic digoxin conce
  • Coronavirus disease 2019 (COVID-19) - Symptoms . . . - BMJ Best Practice
    Coronavirus disease 2019 (COVID-19) is a potentially severe acute respiratory infection Respiratory transmission is the dominant mode of transmission, with proximity and ventilation being the key determinants of transmission risk Transmission is more likely if contacts are exposed shortly before or after symptom onset in the index patient Patients may be minimally symptomatic or
  • Symptoms, diagnosis and treatment - BMJ Best Practice
    Opioid overdose occurs when a person takes opioids in larger quantities than are physically tolerated Signs include central nervous system and respiratory depression, miosis, and apnoea The patient's history from bystanders friends family can assist diagnosis Initial treatment consists of ensu
  • Symptoms, diagnosis and treatment - BMJ Best Practice
    Acute toxicity may occur in adults and children after ingestion of ≥125 mg kg salicylate [2] Chronic poisoning tends to occur after repeated exposure to high-dose aspirin, particularly in people with renal insufficiency
  • Symptoms, diagnosis and treatment - BMJ Best Practice
    Early symptoms are nonspecific and include headache, dizziness, and nausea If symptoms of CO poisoning are suspected, individuals should leave the building or space immediately and call the emergency medical services





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