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  • Home page | Critical Care
    Critical Care, the top open access journal in critical care medicine, advances critically ill patient care with high-quality, evidence-based
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    A pioneering open access journal with a highly respected Editorial Board, Critical Care has been leading its field for more than a decade The journal is
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    Degradation of endothelial glycocalyx provides new insights in the pathogenesis of septic shock microvascular failure Authors: R Nevière, R Favory and X Marechal Citation:Critical Care 2007 11 (Suppl 2):P19 Content type: Poster presentationPublished on: 22 March 2007 View Full Text View PDF
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    Critical Care, the top open access journal in critical care medicine, advances critically ill patient care with high-quality, evidence-based
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    Introduction The cholinergic anti-infl ammatory pathway (CAP) is a physiological mechanism that inhibits cytokine production and minimizes tissue injury during infl ammation CAP-mediated anti-infl ammatory signals in vagal eff erent nerve fi bers result in the release of acetylcholine, which interacts with innate immune cells that express the nicotinic acetylcholine receptor subunit α7
  • REVIEW The fluid management of adults with severe malaria
    Abstract Fluid resuscitation has long been considered a key intervention in the treatment of adults with severe falciparum malaria Profound hypovolemia is common in these patients and has the potential to exacerbate the acidosis and acute kidney injury that are independent predictors of death However, new microvascular imaging techniques have shown that disease severity correlates more
  • Hybrid blood purification strategy in pediatric septic shock
    Gabriella Bottari1* , Fabio Silvio Taccone2and Andrea Moscatelli1 Extracorporeal blood purification techniques (EBTs) are emerging as beneficial interventions in the management of sepsis Although the combination of different EBTs has also been suggested as a poten-tially effective approach in the early phases of sepsis [1, 2], no data are available for pediatric septic shock
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