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rushlight    
n. 灯心草蜡烛;暗淡的灯火

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  • Advanced and metastatic prostate cancer: ESMO Clinical . . .
    This includes metastatic castration-sensitive prostate cancer (mCSPC), non-metastatic castration-resistant prostate cancer (nmCRPC) and metastatic castration-resistant prostate cancer (mCRPC) The management of early-stage disease is covered in the ESMO CPG for local and locoregional prostate cancer 1
  • Overview of systemic treatment for recurrent or metastatic . . .
    The options for initial systemic therapy for advanced, recurrent, and metastatic CSPC are discussed elsewhere; there are also separate discussion of the diagnostic evaluation, local salvage treatments, and the role of systemic therapy for males with a rising serum PSA after definitive local therapy
  • Metastatic Prostate Cancer: Androgen deprivation therapy
    Castration-sensitive prostate carcinoma (CSPC): CSPC is an advanced prostate carcinoma (biochemical progression or proven metastases) with a response to androgen deprivation (see below) Depending on the detection of metastases on imaging, the stage is referred to as M0 CSPC or M1 CSPC It isn't easy to distinguish stage M0 CSPC from a local recurrence after curative therapy Histology and PSA
  • Systemic Therapy in Patients With Metastatic Castration . . .
    Background In 2025, ASCO launched the living clinical practice guideline on systemic therapy in patients with metastatic castration-resistant prostate cancer (CRPC) Based on new evidence, this version of the systemic therapy in patients with metastatic CRPC (mCRPC) living guideline provides updated recommendations based on latest evidence
  • TALZENNA Plus XTANDI Significantly Improves Radiographic . . .
    Prostate cancer is the second most common cancer in men worldwide, with an estimated 1 4 million new cases diagnosed globally in 2022 1 and 330,000 new cases anticipated in the United States in 2026 2 mCSPC, is a form of advanced prostate cancer that has spread beyond the prostate but is still sensitive to androgen inhibition 3 Despite recent
  • Advanced Prostate Cancer: AUA SUO Guideline (2026)
    The management of advanced prostate cancer is rapidly evolving To assist in clinical decision-making, evidence-based guideline statements were developed to provide a rational basis for evidence-based treatment This guideline covers advanced prostate cancer, including disease stages that range from prostate-specific antigen (PSA) recurrence after exhaustion of local treatment options to
  • ADVANCED PROSTATE CANCER
    Metastatic: Cancer has spread to other parts of the body, such as the bones, lymph nodes, lungs, or liver This is also referred to as Stage IV prostate cancer Castration-Sensitive Prostate Cancer (CSPC, also called Hormone-Sensitive Prostate Cancer): A form of prostate cancer that still responds to testosterone suppression therapy
  • Metastatic castration-resistant prostate cancer (mCRPC)
    Overview Metastatic castration-resistant prostate cancer (mCRPC) is prostate cancer that has spread away from the prostate and no longer responds to hormone therapy treatments Hormone therapy for prostate cancer, also called androgen deprivation therapy (ADT), lowers the levels of the hormone testosterone in the body Prostate cancer cells typically use testosterone to help them grow
  • Frontiers | Targeted and immunotherapeutic strategies for . . .
    The disease can be categorized based on its response to ADT: Castration-Sensitive Prostate Cancer (CSPC) and Castration-Resistant Prostate Cancer (CRPC) CSPC is an early stage of metastatic prostate cancer, in which ADT, as an important treatment method for cancer, can effectively inhibit tumor growth by reducing testosterone levels in the body
  • Recent Advances in the Treatment of Metastatic Castration . . .
    Recent Advances in the Treatment of Metastatic Castration-Sensitive Prostate Cancer (mCSPC) | Around the Practice | CancerNetwork is home to the journal Oncology provides insights on the screening, early detection, diagnosis, treatment and prevention of cancers





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