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digitoxin    
毛地黄毒甙; 洋地黄毒甙

毛地黄毒□; 洋地黄毒□

digitoxin
n 1: digitalis preparation used to treat congestive heart
failure or cardiac arrhythmia

digitoxin \dig`i*tox"in\ (d[i^]j`[i^]*t[o^]k"s[i^]n), n. (Chem.)
A steroid glycoside, one of the cardiotonic chemical
substances which is extracted from the foxglove. It is a
white, crystalline substance ({C41H64O13}), and is a
3-substituted triglucoside of a steroid, related structurally
to digitalin and digoxin. It is used as a cardiotonic for
treatment of certain heart conditions, such as congestive
heart failure. Chemically it is

(3[beta],5[beta])-3-[(O-2,6-Dideoxy-[beta]-D-ribo-hexopyranosyl-(1[rarr]4)-O-2,6-dideoxy-[beta]-D-ribo-hexopyranosyl-(1[rarr]4)-2,
6-dideoxy-[beta]-D-ribo-hexopyranosyl)oxy]-14-hydroxy-card-20(22)-enolide.
The related compounds {digitalin} and {digoxin} are also
extracted from the foxglove ({Digitalis lanata} and
{Digitalis purpurea}). The class of steroid glycosides having
cardiotonic properties are refered to as the cardiac
glycoside group. --MI11
[PJC]


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